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pentobarbital will lessen the level or impact of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.

pentobarbital will decrease the level or result of stiripentol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If struggling to avoid coadministration of stiripentol with powerful CYP3A4 inducers, increase stiripentol dose.

fentanyl intranasal and pentobarbital the two increase sedation. Stay clear of or Use Alternate Drug. Restrict use to patients for whom choice remedy options are insufficient

pentobarbital will lower the extent or impact of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Continually observe important symptoms throughout sedation and Restoration time period if coadministered. Thoroughly titrate remimazolam dose if administered with opioid analgesics and/or sedative/hypnotics.

pentobarbital will decrease the level or outcome of vardenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

pentobarbital will minimize the level or impact of colchicine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will reduce the level or result of lefamulin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid coadministration of lefamulin with powerful or moderate CYP3A inducers Except the profit outweighs risks. Watch for diminished efficacy.

pentobarbital will reduce the extent or result of tinidazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will minimize the extent or effect of sufentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.

Cessation of benzodiazepines or other CNS depressants is most popular usually. In some instances, checking at an increased amount of look after tapering CNS depressants might be appropriate. In Many others, little by little tapering a affected individual off of the prescribed benzodiazepine or other CNS depressant or reducing to the lowest helpful dose may very well be correct.

pentobarbital will lower the level or result of tolterodine by influencing hepatic/intestinal here enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will reduce the level or effect of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Strong CYP3A4 inducers may possibly lower midostaurin concentrations resulting in decreased efficacy.

pentobarbital will lower the extent or result of estradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.